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本设计介绍了年产1亿阿昔洛韦咀嚼片的生产工艺设计，本项目生产以阿昔洛韦为主要原料经酯化、氢化反应得到粗品，在经精化得到产品。其中酯化反应产率为90%，氢化反应产率为90%，根据理论计算设计生产工艺。
本设计说明书正文部分包括伐昔洛韦的产品概述、工艺路线论述、全流程物料衡算、设备选型与计算、车间布置设计、工程经济等内容，并绘制了一系列相关的工艺图，本设计是初次设计，简单设计了生产伐昔洛韦的运用较广的生产工艺，设计思虑如下：物料衡算，先根据生产要求，以两天一批算出每批成品量，求出每批需投入的原料量，在进行其他原料、中间产品等的计算。设备的选型与校核实根据物料衡算来设计的，车间设备布置详见附表。设计任务时间紧再加上设计经验不足，难免有错误之处，望老师批评指正。
关键词：阿昔洛韦；咀嚼片；工艺设计；物料衡算
This design introduces the production process design of 100 million acyclovir chewable tablets per year. In this project, acyclovir is used as the main raw material to get crude products by esterification and hydrogenation. The yield of esterification reaction and hydrogenation reaction were 90 and 90 respectively. According to the theoretical calculation, the production process was designed.
The main body part of this design instruction includes the product overview , process route discussion , whole process material balance calculation , equipment selection and calculation , workshop layout design , engineering economy , etc . Task time, coupled with the design experience, there are inevitably mistakes, I hope teachers criticize and correct.
Keywords: acyclovir; chewable tablets; process design; material balance
目 录
7. 质量控制要点一览表、工艺员查证内容、质量检查员检查内容19
